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8TCI

Crystal structure of DNMT3C-DNMT3L in complex with CGG DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
DNA (cytosine-5)-methyltransferase 3Cpolymer28432535.52UniProt (P0DOY1)
Pfam (PF00145)
Mus musculus (house mouse)Dnmt3c
2B, C
(B, C)
DNA (cytosine-5)-methyltransferase 3-likepolymer19923024.42UniProt (Q9UJW3)Homo sapiens (human)
3E, F
(E, F)
(5'-D(P*CP*AP*TP*G)-R(P*(PYO))-D(P*GP*GP*TP*CP*TP*AP*AP*TP*TP*AP*GP*AP*CP*CP*GP*CP*AP*TP*G)-3')polymer247370.82Mus musculus
4G, H
(A, D)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
Sequence modifications
A, D: 458 - 740 (UniProt: P0DOY1)
PDBExternal DatabaseDetails
Ser 457-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight125861.3
Non-Polymers*Number of molecules2
Total formula weight768.8
All*Total formula weight126630.2
*Water molecules are not included.

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PDB entries from 2025-12-17

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