8TCI

Crystal structure of DNMT3C-DNMT3L in complex with CGG DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	DNA (cytosine-5)-methyltransferase 3C	polymer	284	32535.5	2	UniProt (P0DOY1) Pfam (PF00145) In PDB	Mus musculus (house mouse)	Dnmt3c
2	B, C	DNA (cytosine-5)-methyltransferase 3-like	polymer	199	23024.4	2	UniProt (Q9UJW3) In PDB	Homo sapiens (human)
3	E, F	(5'-D(P*CP*AP*TP*G)-R(P*(PYO))-D(P*GP*GP*TP*CP*TP*AP*AP*TP*TP*AP*GP*AP*CP*CP*GP*CP*AP*TP*G)-3')	polymer	24	7370.8	2		Mus musculus
4	A, D	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)

Sequence modifications

A, D: 458 - 740 (UniProt: P0DOY1)

PDB	External Database	Details
Ser 457	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	125861.3
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	126630.2

*Water molecules are not included.