8TCG
Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Integrin alpha-V heavy chain | polymer | 440 | 47898.0 | 1 | UniProt (P06756) Pfam (PF01839) In PDB | Homo sapiens (human) | |
2 | B | Integrin beta-6 | polymer | 242 | 26948.7 | 1 | UniProt (P18564) Pfam (PF00362) In PDB | Homo sapiens (human) | |
3 | C | Minibinder B6_BP_dslf | polymer | 72 | 8415.7 | 1 | synthetic construct | ||
4 | D | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
5 | A | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | B | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) |
Sequence modifications
A: 1 - 440 (UniProt: P06756)
B: 113 - 354 (UniProt: P18564)
PDB | External Database | Details |
---|---|---|
Gly 400 | - | insertion |
Cys 401 | Met 430 | conflict |
PDB | External Database | Details |
---|---|---|
Cys 270 | Ile 287 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 83262.5 | |
Branched | Number of molecules | 1 |
Total formula weight | 748.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 767.5 | |
All* | Total formula weight | 84778.7 |