8TCB

Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M87 protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	C4b-binding protein alpha chain	polymer	128	14163.9	2	UniProt (P04003) Pfam (PF00084)	Homo sapiens (human)	C4bp,Proline-rich protein,PRP
2	B, C (C, D)	M protein	polymer	104	12531.7	2	UniProt (Q6TLP8) UniProt (by SIFTS) (W0T311)	Streptococcus pyogenes
3	E (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
4	F, G, H, I (A, C, D, B)	water	water		18.0	29	Chemie (HOH)

Sequence modifications

A, B: 1 - 124 (UniProt: P04003)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

C, D: 42 - 141 (UniProt: Q6TLP8)

PDB	External Database	Details
Gly 38	-	expression tag
Pro 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53391.1
Non-Polymers*	Number of molecules	1
	Total formula weight	39.1
All*	Total formula weight	53430.2

*Water molecules are not included.