8TC6
Sequence specific (AATT and TGTCA) orientation of netropsin and ImPyPy molecules at two unique minor groove binding sites within a self-assembled 3D DNA lattice (4x5)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*TP*GP*TP*CP*AP*C*(NT))-3') | polymer | 21 | 6457.2 | 1 | synthetic construct | ||
| 2 | B | DNA (5'-D(P*CP*GP*TP*CP*A)-3') | polymer | 5 | 1480.0 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(*TP*CP*GP*TP*GP*AP*CP*AP*T)-3') | polymer | 9 | 2730.8 | 1 | synthetic construct | ||
| 4 | D | DNA (5'-D(P*GP*GP*TP*CP*TP*GP*C)-3') | polymer | 7 | 2129.4 | 1 | synthetic construct | ||
| 5 | A | NETROPSIN | non-polymer | 430.5 | 1 | Chemie (NT) | |||
| 6 | A, C | N-[5-({5-[(3-{[3-(dimethylamino)propyl]amino}-3-oxopropyl)carbamoyl]-1-methyl-1H-pyrrol-3-yl}carbamoyl)-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-imidazole-2-carboxamide | non-polymer | 525.6 | 2 | Chemie (ZQQ) | |||
| 7 | B, D | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 8 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 12797.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1755.6 | |
| All* | Total formula weight | 14553.1 |
