8T9H
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3.2 | polymer | 135 | 15303.9 | 2 | UniProt (P84233) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | Histone H3 |
2 | B, F | Histone H4 | polymer | 103 | 11396.4 | 2 | UniProt (A0A8J1LTD2) Pfam (PF15511) UniProt (by SIFTS) (P62799) In PDB | Xenopus laevis (African clawed frog) | |
3 | C, G | Histone H2A | polymer | 130 | 14109.4 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB | Xenopus laevis (African clawed frog) | |
4 | D, H | Histone H2B 1.1 | polymer | 123 | 13655.9 | 2 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | H2B1.1 |
5 | I | DNA (146-MER) | polymer | 146 | 44824.6 | 1 | Escherichia coli 'BL21-Gold(DE3)pLysS AG' | ||
6 | J | DNA (146-MER) | polymer | 146 | 45304.9 | 1 | Escherichia coli 'BL21-Gold(DE3)pLysS AG' | ||
7 | K | Histone-lysine N-methyltransferase KMT5B | polymer | 394 | 44703.1 | 1 | UniProt (Q4FZB7) Pfam (PF00856) In PDB | Homo sapiens (human) |
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
B, F: 0 - 102 (UniProt: A0A8J1LTD2)
D, H: 4 - 125 (UniProt: P02281)
K: 2 - 393 (UniProt: Q4FZB7)
PDB | External Database | Details |
---|---|---|
Ala 102 | Gly 103 | variant |
PDB | External Database | Details |
---|---|---|
Met 20 | Lys 34 | conflict |
PDB | External Database | Details |
---|---|---|
Met 3 | - | initiating methionine |
Thr 32 | Ser 33 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 243764.0 | |
All* | Total formula weight | 243764.0 |