8T83
X-ray crystal structure of PfA-M1(M462K)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aminopeptidase N | polymer | 898 | 104832.0 | 1 | UniProt (O96935) Pfam (PF17900) Pfam (PF01433) Pfam (PF11940) Pfam (PF17432) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | M1 alanyl aminopeptidase,PfM1AAP,M1 family aminopeptidase,PfA-M1 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | water | water | 18.0 | 585 | Chemie (HOH) |
Sequence modifications
A: 195 - 1085 (UniProt: O96935)
PDB | External Database | Details |
---|---|---|
Met 194 | - | initiating methionine |
Gln 213 | Asn 213 | conflict |
Gln 223 | Asn 223 | conflict |
Pro 378 | His 378 | conflict |
Lys 462 | Met 462 | engineered mutation |
Gln 501 | Asn 501 | conflict |
Gln 745 | Asn 745 | conflict |
Gln 795 | Asn 795 | conflict |
Gln 1069 | Asn 1069 | conflict |
His 1086 | - | expression tag |
His 1087 | - | expression tag |
His 1088 | - | expression tag |
His 1089 | - | expression tag |
His 1090 | - | expression tag |
His 1091 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 104832.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 341.7 | |
All* | Total formula weight | 105173.6 |