8T6V
Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Band 3 anion transport protein | polymer | 523 | 58254.1 | 2 | UniProt (P02730) Pfam (PF00955) | Homo sapiens (human) | Anion exchange protein 1,AE 1,Anion exchanger 1,Solute carrier family 4 member 1 |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, K (A, B) | 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid | non-polymer | 454.5 | 2 | Chemie (4DS) | |||
| 4 | F, H, I, L, N... (A, B) | CHOLESTEROL | non-polymer | 386.7 | 6 | Chemie (CLR) | |||
| 5 | G, M (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 6 | J, P (B) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) | |||
| 7 | Q, R (A, B) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116508.2 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5782.7 | |
| All* | Total formula weight | 123139.7 |
