8T6K
Cryo-EM structure of tetradecameric CaMKII beta holoenzyme T287A T306A T307A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Venus-tagged CaMKII Beta Holoenzyme mutant | polymer | 815 | 90846.9 | 14 | UniProt (P42212) UniProt (P08413) Pfam (PF01353) Pfam (PF00069) Pfam (PF08332) In PDB | Aequorea victoria (Water jellyfish Mesonema victoria) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N: -251 - -15 (UniProt: P42212)
A, B, C, D, E, F, G, H, I, J, K, L, M, N: 1 - 542 (UniProt: P08413)
PDB | External Database | Details |
---|---|---|
Met -272 | - | initiating methionine |
Gly -271 | - | expression tag |
Ser -270 | - | expression tag |
Ser -269 | - | expression tag |
His -268 | - | expression tag |
His -267 | - | expression tag |
His -266 | - | expression tag |
His -265 | - | expression tag |
His -264 | - | expression tag |
His -263 | - | expression tag |
Ser -262 | - | expression tag |
Ser -261 | - | expression tag |
Gly -260 | - | expression tag |
Leu -259 | - | expression tag |
Val -258 | - | expression tag |
Pro -257 | - | expression tag |
Arg -256 | - | expression tag |
Gly -255 | - | expression tag |
Ser -254 | - | expression tag |
His -253 | - | expression tag |
Val -252 | - | expression tag |
Leu -207 | Phe 46 | conflict |
Leu -189 | Phe 64 | conflict |
Gly -188 | Ser 65 | conflict |
Leu -185 | Val 68 | conflict |
Ala -181 | Ser 72 | conflict |
Thr -100 | Met 153 | conflict |
Ala -90 | Val 163 | conflict |
Gly -78 | Ser 175 | conflict |
Tyr -50 | Thr 203 | conflict |
Lys -47 | Ala 206 | conflict |
Leu -22 | His 231 | conflict |
Ser -14 | - | linker |
Gly -13 | - | linker |
Leu -12 | - | linker |
Arg -11 | - | linker |
Ser -10 | - | linker |
Arg -9 | - | linker |
Ala -8 | - | linker |
Gln -7 | - | linker |
Ala -6 | - | linker |
Ser -5 | - | linker |
Asn -4 | - | linker |
Ser -3 | - | linker |
Ala -2 | - | linker |
Val -1 | - | linker |
Asp 0 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 287 | Thr 287 | engineered mutation |
Ala 306 | Thr 306 | engineered mutation |
Ala 307 | Thr 307 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 14 |
Total formula weight | 1271856.0 | |
All* | Total formula weight | 1271856.0 |