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8T0S

Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitin-conjugating enzyme E2 G2polymer16518713.41UniProt (P60604)
Pfam (PF00179)
Homo sapiens (human)E2 ubiquitin-conjugating enzyme G2,Ubiquitin carrier protein G2,Ubiquitin-protein ligase G2
2B
(B)
E3 ubiquitin-protein ligase AMFRpolymer273365.91UniProt (Q9UKV5)
Pfam (PF18442)
Homo sapiensAutocrine motility factor receptor,AMF receptor,RING finger protein 45,gp78
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D, E
(A, B)
waterwater18.0167Chemie (HOH)
Sequence modifications
A: 1 - 165 (UniProt: P60604)
PDBExternal DatabaseDetails
Ser 75Cys 75engineered mutation
Ser 89Cys 89engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight22079.3
Non-Polymers*Number of molecules1
Total formula weight62.1
All*Total formula weight22141.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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