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8SXO

Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164I Mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3C-like proteinase nsp5polymer30633800.61UniProt (P0DTC1)
Pfam (PF05409)
UniProt (by SIFTS) (P0DTD1)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)3CL-PRO, 3CLp, Main protease, Mpro, Non-structural protein 5, nsp5, SARS coronavirus main proteinase
2B
(A)
waterwater18.010Chemie (HOH)
Sequence modifications
A: 1 - 306 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Ile 164His 3427engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33800.6
All*Total formula weight33800.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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