8SXJ

CH505 Disulfide Stapled SOSIP Bound to CH235.12 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I	Envelope glycoprotein gp160	polymer	456	51446.8	3	UniProt (M4M3Q1) Pfam (PF00516) In PDB	Human immunodeficiency virus 1	Env polyprotein
2	B, F, J	HIV-1 gp41	polymer	126	14265.1	3		Human immunodeficiency virus 1
3	C, G, K	CH235.12 Heavy Chain	polymer	122	13723.4	3		Homo sapiens
4	D, H, L	CH235.12 Light Chain	polymer	105	11561.8	3		Homo sapiens

Sequence modifications

A, E, I: 35 - 504 (UniProt: M4M3Q1)

PDB	External Database	Details
Glu 32	-	expression tag
Asn 33	-	expression tag
Leu 34	-	expression tag
Ile 68	Val 64	conflict
Cys 127	Val 123	conflict
Cys 167	Asp 154	conflict
Asp 197	Asn 184	conflict
Val 204	Ala 191	conflict
Leu 208	Val 195	conflict
Leu 255	Val 242	conflict
Lys 279	Asn 266	conflict
Tyr 458	Gly 437	conflict
Lys 488	Glu 467	conflict
Ile 489	Val 468	conflict
Glu 490	Lys 469	conflict
Arg 498	Asn 477	conflict
Cys 499	Ala 478	conflict
Lys 500	Arg 479	conflict

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	272991.4
All*	Total formula weight	272991.4

*Water molecules are not included.