8SWR
Structure of K. lactis PNP S42E variant bound to transition state analog DADMe-IMMUCILLIN G and sulfate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Purine nucleoside phosphorylase | polymer | 308 | 33668.4 | 6 | UniProt (Q6CSZ6) Pfam (PF01048) | Kluyveromyces lactis NRRL Y-1140 | |
| 2 | G, I, J (A, B, D) | 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one | non-polymer | 279.3 | 3 | Chemie (IM5) | |||
| 3 | H, K (A, D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | L (E) | GUANINE | non-polymer | 151.1 | 1 | Chemie (GUN) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 306 (UniProt: Q6CSZ6)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Glu 42 | Ser 42 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 202010.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1181.1 | |
| All* | Total formula weight | 203191.4 |
