8SWC
RNase H complex with ASO (OOO) and RNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ribonuclease H1 | polymer | 294 | 33218.5 | 1 | UniProt (O60930) Pfam (PF01693) Pfam (PF00075) In PDB | Homo sapiens (human) | RNase H1,Ribonuclease H type II |
2 | B | RNA (5'-R(*UP*GP*GP*CP*GP*AP*GP*UP*GP*GP*GP*UP*GP*AP*GP*UP*GP*AP*GP*G)-3') | polymer | 20 | 6615.0 | 1 | Homo sapiens | ||
3 | C | PO ASO | polymer | 20 | 6380.3 | 1 | Homo sapiens | ||
4 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
5 | A, B | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
6 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
7 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 1 - 286 (UniProt: O60930)
PDB | External Database | Details |
---|---|---|
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Asn 210 | Asp 210 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 46213.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 406.2 | |
All* | Total formula weight | 46620.0 |