8SWB
RNase H complex with streopure ASO and RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ribonuclease H1 | polymer | 149 | 16575.7 | 1 | UniProt (O60930) Pfam (PF00075) | Homo sapiens (human) | RNase H1,Ribonuclease H type II |
| 2 | B (B) | RNA (5'-R(*UP*GP*GP*CP*GP*AP*GP*UP*GP*GP*GP*UP*GP*AP*GP*UP*GP*AP*GP*G)-3') | polymer | 20 | 6615.0 | 1 | Homo sapiens | ||
| 3 | C (D) | DNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*AP*(SC)P*(SC)P*(RC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3') | polymer | 20 | 6621.3 | 1 | Homo sapiens | ||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | F (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | G, H, I (A, B, D) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 137 - 285 (UniProt: O60930)
| PDB | External Database | Details |
|---|---|---|
| Asn 210 | Asp 210 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 29812.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 293.2 | |
| All* | Total formula weight | 30105.2 |
