8SW4
BG505 GT1.1 SOSIP in complex with NHP Fabs 21N13, 21M20 and RM20A3
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | 21M20 heavy chain variable region | polymer | 125 | 13737.4 | 1 | Macaca | ||
2 | L | 21M20 light chain variable region | polymer | 107 | 11358.6 | 1 | Macaca | ||
3 | A, C, D | BG505 GT1.1 SOSIP gp120 | polymer | 509 | 57275.5 | 3 | Human immunodeficiency virus 1 | ||
4 | B, G, I | Envelope glycoprotein gp41 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S6) Pfam (PF00517) In PDB | Human immunodeficiency virus 1 | Env polyprotein |
5 | E, J, K | RM20A3 heavy chain variable region | polymer | 124 | 13424.0 | 3 | Macaca | ||
6 | F, M, N | RM20A3 light chain variable region | polymer | 111 | 11755.8 | 3 | Macaca | ||
7 | O, Q, S | 21N13 heavy chain variable region | polymer | 130 | 14476.9 | 3 | Macaca | ||
8 | P, R, T | 21N13 light chain variable region | polymer | 107 | 11757.1 | 3 | Macaca | ||
9 | U, W, X | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
10 | V | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
11 | A, D, I, B, C... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 33 | Chemie (NAG) |
Sequence modifications
B, G, I: 512 - 664 (UniProt: Q2N0S6)
PDB | External Database | Details |
---|---|---|
Pro 559 | Ile 556 | engineered mutation |
Cys 605 | Thr 602 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 20 |
Total formula weight | 402603.3 | |
Branched | Number of molecules | 4 |
Total formula weight | 2670.4 | |
Non-Polymers* | Number of molecules | 33 |
Total formula weight | 7299.9 | |
All* | Total formula weight | 412573.7 |