8SW3
BG505 GT1.1 SOSIP in complex with NHP Fabs 12C11 and RM20A3
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (A, C, D) | BG505 GT1.1 SOSIP gp120 | polymer | 509 | 57275.5 | 3 | Human immunodeficiency virus 1 | ||
| 2 | B, H, N (G, J, K) | RM20A3 heavy chain variable region | polymer | 125 | 13511.1 | 3 | Macaca | ||
| 3 | C, I, O (I, O, P) | RM20A3 light chain variable region | polymer | 111 | 11755.8 | 3 | Macaca | ||
| 4 | D, J, P (B, E, F) | Envelope glycoprotein gp41 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S6) Pfam (PF00517) | Human immunodeficiency virus 1 | Env polyprotein |
| 5 | E, K, Q (H, M, N) | 12C11 heavy chain variable region | polymer | 130 | 14244.8 | 3 | Macaca | ||
| 6 | F, L, R (L, Q, R) | 12C11 light chain variable region | polymer | 110 | 11475.5 | 3 | Macaca | ||
| 7 | S, U, W (S, U, W) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 8 | T, V, X (T, V, X) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 9 | AA, AB, BA, BB, CA... (A, D, B, F, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 42 | Chemie (NAG) |
Sequence modifications
B, E, F: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | engineered mutation |
| Cys 605 | Thr 602 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 376227.6 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3519.2 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 9290.7 | |
| All* | Total formula weight | 389037.6 |
