8SVY
MBP-Mcl1 in complex with ligand 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Maltose/maltodextrin-binding periplasmic protein, Induced myeloid leukemia cell differentiation protein Mcl-1 chimera | polymer | 518 | 57310.9 | 1 | UniProt (P0AEY0) UniProt (Q07820) Pfam (PF01547) Pfam (PF00452) UniProt (by SIFTS) (P0AEX9) In PDB | Escherichia coli | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | R | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | A | (15P)-17-chloro-33-fluoro-12-[(2-methoxyethoxy)methyl]-5,14,22-trimethyl-28-oxa-9-thia-5,6,13,14,22-pentaazaheptacyclo[27.7.1.1~4,7~.0~11,15~.0~16,21~.0~20,24~.0~30,35~]octatriaconta-1(36),4(38),6,11(15),12,16,18,20,23,29(37),30,32,34-tridecaene-23-carboxylic acid | non-polymer | 746.3 | 1 | Chemie (WUC) | |||
| 6 | water | water | 18.0 | 672 | Chemie (HOH) |
Sequence modifications
A: -195 - 170 (UniProt: P0AEY0)
A: 173 - 321 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly -196 | - | expression tag |
| Gly 171 | - | linker |
| Ser 172 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 194 | Lys 194 | conflict |
| Ala 197 | Lys 197 | conflict |
| Ala 201 | Arg 201 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57310.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1086.7 | |
| All* | Total formula weight | 58739.8 |
