8SVN

Crystal structure of the apo form of pregnane X receptor ligand binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Pregnane X receptor ligand binding domain fused to SRC-1 coactivator peptide	polymer	351	39895.6	2	UniProt (O75469) UniProt (Q15788) Pfam (PF00104) Pfam (PF08832)	Homo sapiens (human)
2	C, D (A, B)	water	water		18.0	72	Chemie (HOH)

Sequence modifications

A, B: 130 - 434 (UniProt: O75469)

PDB	External Database	Details
His 123	-	expression tag
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
Gly 129	-	expression tag
Ser 435	-	linker
Gly 436	-	linker
Gly 437	-	linker
Ser 438	-	linker
Gly 439	-	linker
Gly 440	-	linker

A, B: 441 - 473 (UniProt: Q15788)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79791.3
All*	Total formula weight	79791.3

*Water molecules are not included.