8STH
human STING with diABZI agonist 15
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Stimulator of interferon genes protein | polymer | 187 | 21489.2 | 1 | UniProt (Q86WV6) Pfam (PF15009) In PDB | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | A | 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide | non-polymer | 782.8 | 1 | Chemie (WWU) | |||
| 3 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 153 - 339 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Arg 232 | His 232 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21489.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 782.8 | |
| All* | Total formula weight | 22272.0 |
