8STC
S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with Zinc and soaked with bicarbonate.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Pyridinium-3,5-biscarboxylic acid mononucleotide synthase | polymer | 256 | 26494.2 | 6 | UniProt (F9UST0) Pfam (PF00731) In PDB | Lactiplantibacillus plantarum WCFS1 | P2CMN synthase,Lactate racemase accessory protein LarB,Lactate racemase activation protein LarB,Lactate racemase maturation protein LarB,Lactate racemization operon protein LarB,Nickel-pincer cofactor biosynthesis protein LarB,Nicotinic acid adenine dinucleotide carboxylase/hydrolase,NaAD carboxylase/hydrolase |
2 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F: 1 - 246 (UniProt: F9UST0)
PDB | External Database | Details |
---|---|---|
Ala 127 | Ser 127 | engineered mutation |
Ala 247 | - | expression tag |
Ser 248 | - | expression tag |
Trp 249 | - | expression tag |
Ser 250 | - | expression tag |
His 251 | - | expression tag |
Pro 252 | - | expression tag |
Gln 253 | - | expression tag |
Phe 254 | - | expression tag |
Glu 255 | - | expression tag |
Lys 256 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 158965.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 179.4 | |
All* | Total formula weight | 159144.8 |