8ST8

Structure of E3 ligase SopA bound to ubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 ubiquitin-protein ligase SopA	polymer	197	22017.7	1	UniProt (Q8ZNR3) Pfam (PF13979)	Salmonella enterica subsp. enterica serovar Typhimurium	HECT-type E3 ubiquitin transferase SopA,Salmonella outer protein A,Secreted effector protein SopA
2	B (B)	Ubiquitin	polymer	75	8519.8	1	UniProt (P0CG48) Pfam (PF00240)	Homo sapiens (human)
3	C (A)	prop-2-en-1-amine	non-polymer		57.1	1	Chemie (AYE)
4	D, E (A, B)	water	water		18.0	218	Chemie (HOH)

Sequence modifications

A: 603 - 782 (UniProt: Q8ZNR3)

PDB	External Database	Details
His 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
Ser 592	-	expression tag
Ser 593	-	expression tag
Gly 594	-	expression tag
Leu 595	-	expression tag
Glu 596	-	expression tag
Val 597	-	expression tag
Leu 598	-	expression tag
Phe 599	-	expression tag
Gln 600	-	expression tag
Gly 601	-	expression tag
Pro 602	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30537.5
Non-Polymers*	Number of molecules	1
	Total formula weight	57.1
All*	Total formula weight	30594.6

*Water molecules are not included.