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8SRK

Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
TRPM2 chanzymepolymer1214137394.24UniProt (F2UB89)
Pfam (PF18139)
Pfam (PF00520)
Salpingoeca rosettaNudt9 protein
2E, K, Q, Y
(A, B, C, D)
ADENOSINE-5-DIPHOSPHORIBOSEnon-polymer559.34Chemie (APR)
3AA, F, G, L, M...
(D, A, B, C)
CALCIUM IONnon-polymer40.18Chemie (CA)
4BA, H, I, J, N...
(D, A, B, C)
CHOLESTEROLnon-polymer386.712Chemie (CLR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight549576.7
Non-Polymers*Number of molecules24
Total formula weight7197.7
All*Total formula weight556774.4
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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