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8SRE

Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, D, B, C)
TRPM2 chanzymepolymer1494168252.54UniProt (F2UB89)
Pfam (PF18139)
Pfam (PF00520)
Salpingoeca rosettaNudt9 protein
2E, GA, L, LA, R...
(A, B, C, D)
ADENOSINE-5-DIPHOSPHORIBOSEnon-polymer559.38Chemie (APR)
3AA, BA, CA, DA, EA...
(B, A, C, D)
MAGNESIUM IONnon-polymer24.321Chemie (MG)
4FA, HA, IA, JA, K...
(B, C, A, D)
CHOLESTEROLnon-polymer386.712Chemie (CLR)
5TA, UA, VA, WA
(A, D, B, C)
waterwater18.012Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight673009.9
Non-Polymers*Number of molecules41
Total formula weight9624.8
All*Total formula weight682634.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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