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8SRC

Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
TRPM2 chanzymepolymer1494168252.54UniProt (F2UB89)
Pfam (PF18139)
Pfam (PF00520)
Salpingoeca rosettaTRPM2 chanzyme
2DA, E, IA, K, O...
(C, A, D, B)
ADENOSINE-5-DIPHOSPHORIBOSEnon-polymer559.38Chemie (APR)
3AA, BA, F, G, H...
(C, A, D, B)
CALCIUM IONnon-polymer40.117Chemie (CA)
4CA, EA, FA, GA, HA...
(C, D, A, B)
CHOLESTEROLnon-polymer386.712Chemie (CLR)
5PA, QA, RA, SA
(A, B, C, D)
waterwater18.04Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight673009.9
Non-Polymers*Number of molecules37
Total formula weight9795.7
All*Total formula weight682805.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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