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8SR7

Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
TRPM2 Chanzymepolymer1494168252.54UniProt (F2UB89)
Pfam (PF18139)
Pfam (PF00520)
Salpingoeca rosettaTRPM2 chanzyme
2E, IA, O, X
(A, D, B, C)
5-O-phosphono-beta-D-ribofuranosenon-polymer230.14Chemie (RP5)
3F, JA, P, Y
(A, D, B, C)
ADENOSINE MONOPHOSPHATEnon-polymer347.24Chemie (AMP)
4AA, BA, CA, G, H...
(C, A, D, B)
MAGNESIUM IONnon-polymer24.317Chemie (MG)
5DA, EA, FA, GA, HA...
(C, D, A, B)
CHOLESTEROLnon-polymer386.712Chemie (CLR)
6PA, QA, RA, SA
(A, B, C, D)
waterwater18.052Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight673009.9
Non-Polymers*Number of molecules37
Total formula weight7362.4
All*Total formula weight680372.3
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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