8SQ8
X-ray crystal structure of Acinetobacter baumanii beta-lactamase variant OXA-109 in complex with doripenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase OXA-109 | polymer | 250 | 28170.1 | 4 | UniProt (A8JZR7) Pfam (PF00905) | Acinetobacter baumannii | Carbapenem-hydrolyzing oxacillinase |
| 2 | E, F, H, I (A, B, C, D) | (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 422.5 | 4 | Chemie (4J6) | |||
| 3 | G, J (B, D) | BICARBONATE ION | non-polymer | 61.0 | 2 | Chemie (BCT) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 26 - 274 (UniProt: A8JZR7)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112680.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1812.1 | |
| All* | Total formula weight | 114492.6 |
