8SOS

Human CD1d presenting sphingomyelin C24:1 in complex with VHH nanobody 1D17

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, E)	Antigen-presenting glycoprotein CD1d	polymer	347	39471.6	2	UniProt (P15813) Pfam (PF16497) Pfam (PF07654) Pfam (PF00170) UniProt (by SIFTS) (P05412)	Homo sapiens (human)	R3G1
2	B, E (B, F)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C, F (D, G)	Nanobody VHH ID17	polymer	127	13879.7	2		Lama glama (llama)
4	G, J (A, E)	sphingomyelin	non-polymer		814.2	2	Chemie (FO4)
5	H, I, K, L (A, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
6	M, N, O, P, Q... (A, B, D, E, F...)	water	water		18.0	572	Chemie (HOH)

Sequence modifications

A, E: 5 - 278 (UniProt: P15813)

PDB	External Database	Details
Met 4	-	initiating methionine

A, E: 279 - 350 (PDB: 8SOS)
B, F: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	130461.2
Non-Polymers*	Number of molecules	6
	Total formula weight	2513.3
All*	Total formula weight	132974.5

*Water molecules are not included.