8SMP

Xenopus laevis hyaluronan synthase 1, UDP-bound, gating loop inserted state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hyaluronan synthase 1	polymer	601	70385.0	1	UniProt (P13563) Pfam (PF13641)	Xenopus laevis (African clawed frog)	DG42 protein,Hyaluronate synthase 1,Hyaluronic acid synthase 1,HA synthase 1,xHAS1
2	B (H)	Fab15 heavy chain	polymer	234	24674.4	1		Homo sapiens
3	C (L)	Fab15 light chain	polymer	215	23258.8	1		Homo sapiens
4	D (A)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	1	Chemie (UDP)
5	E (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

A: 1 - 588 (UniProt: P13563)

PDB	External Database	Details
Met -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	118318.2
Non-Polymers*	Number of molecules	2
	Total formula weight	428.5
All*	Total formula weight	118746.7

*Water molecules are not included.