8SLU
Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 5 | polymer | 282 | 32518.0 | 1 | UniProt (P54829) Pfam (PF00102) | Homo sapiens (human) | Neural-specific protein-tyrosine phosphatase,Striatum-enriched protein-tyrosine phosphatase,STEP |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 256 - 537 (UniProt: P54829)
| PDB | External Database | Details |
|---|---|---|
| Met 257 | Ala 281 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32518.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 284.2 | |
| All* | Total formula weight | 32802.2 |
