8SKU
Structure of human SIgA1 in complex with human CD89 (FcaR1)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, G (A, B, C, D) | Immunoglobulin heavy constant alpha 1 | polymer | 353 | 37687.5 | 4 | UniProt (P01876) Pfam (PF07654) Pfam (PF00047) | Homo sapiens (human) | Ig alpha-1 chain C region,Ig alpha-1 chain C region BUR,Ig alpha-1 chain C region TRO |
| 2 | C (E) | Secretory component | polymer | 553 | 61095.6 | 1 | UniProt (P01833) Pfam (PF07686) | Homo sapiens (human) | Polymeric immunoglobulin receptor |
| 3 | D, F (R, S) | Immunoglobulin alpha Fc receptor | polymer | 207 | 23615.7 | 2 | UniProt (P24071) Pfam (PF00047) | Homo sapiens (human) | IgA Fc receptor, CD89 |
| 4 | H (J) | Immunoglobulin J chain | polymer | 137 | 15611.5 | 1 | UniProt (P01591) Pfam (PF15097) | Homo sapiens (human) | Joining chain of multimeric IgA and IgM |
| 5 | I, J, K, L (L, I, K, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 6 | M, N, O, P (A, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
E: 1 - 547 (UniProt: P01833)
R, S: 1 - 195 (UniProt: P24071)
| PDB | External Database | Details |
|---|---|---|
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 196 | - | expression tag |
| Ile 197 | - | expression tag |
| Asp 198 | - | expression tag |
| Gly 199 | - | expression tag |
| Arg 200 | - | expression tag |
| Ala 201 | - | expression tag |
| His 202 | - | expression tag |
| His 203 | - | expression tag |
| His 204 | - | expression tag |
| His 205 | - | expression tag |
| His 206 | - | expression tag |
| His 207 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 274688.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 277270.9 |
