8SK0

Crystal structure of EvdS6 decarboxylase in ligand bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	dTDP-glucose 4,6-dehydratase	polymer	348	37770.4	2	UniProt (A0A1C5ADV9) Pfam (PF16363)	Micromonospora carbonacea	Glucuronic acid decarboxylase
2	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	E, H (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
4	F (A)	THYMIDINE-5'-DIPHOSPHATE	non-polymer		402.2	1	Chemie (TYD)
5	G (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6	I (B)	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)
7	J, K (A, B)	water	water		18.0	830	Chemie (HOH)

Sequence modifications

A, B: 7 - 329 (UniProt: A0A1C5ADV9)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Val 1	-	expression tag
Pro 2	-	expression tag
Arg 3	-	expression tag
Val 4	-	expression tag
Phe 5	-	expression tag
Val 6	-	expression tag
Gly 51	Glu 46	conflict
Ser 235	Pro 230	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75540.7
Non-Polymers*	Number of molecules	7
	Total formula weight	2208.4
All*	Total formula weight	77749.2

*Water molecules are not included.