8SJJ

X-ray structure of the metastable SEPT14-SEPT7 heterodimeric coiled coil

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Septin-14	polymer	75	9249.5	2	UniProt (Q6ZU15)	Homo sapiens (human)
2	C, D (C, D)	Septin 7	polymer	88	10935.5	2	UniProt (A0A023T695) UniProt (by SIFTS) (Q16181)	Homo sapiens (human)
3	E, F, H, J, K... (A, B, C, D)	SODIUM ION	non-polymer		23.0	8	Chemie (NA)
4	G, I (B, C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	247	Chemie (HOH)

Sequence modifications

A, B: 1 - 70 (UniProt: Q6ZU15)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Trp 0	-	expression tag

C, D: -12 - 71 (UniProt: A0A023T695)

PDB	External Database	Details
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	40370.1
Non-Polymers*	Number of molecules	10
	Total formula weight	396.2
All*	Total formula weight	40766.2

*Water molecules are not included.