8SIY

Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Leucine-rich repeat and WD repeat-containing protein 1	polymer	651	71651.5	1	UniProt (A0A140UHX1) Pfam (PF00400)	Rattus norvegicus (Norway rat)	Origin recognition complex-associated protein
2	B, F (C, G)	Histone H3.2	polymer	135	15303.9	2	UniProt (P84233) Pfam (PF00125)	Xenopus laevis (African clawed frog)	Histone H3
3	C, G (D, H)	Histone H4	polymer	102	11323.4	2	UniProt (A0A8J1LTD2) Pfam (PF15511) UniProt (by SIFTS) (P62799)	Xenopus laevis (African clawed frog)
4	D, H (E, I)	Histone H2A	polymer	129	13962.2	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211)	Xenopus laevis (African clawed frog)	Histone H2A type 1
5	E, I (F, J)	Histone H2B	polymer	122	13524.8	2	UniProt (P02281) Pfam (PF00125)	Xenopus laevis (African clawed frog)	H2B1.1
6	J (K)	Widom 601 DNA	polymer	153	46998.9	1		synthetic construct
7	K (L)	Widom 601 DNA	polymer	153	47457.2	1		synthetic construct
8	L (B)	Origin recognition complex subunit 2	polymer	103	11570.1	1	UniProt (Q75PQ8)	Rattus norvegicus (Norway rat)

Sequence modifications

A: 1 - 648 (UniProt: A0A140UHX1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

C, G: 1 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	variant

E, I: 1 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	conflict

F, J: 4 - 125 (UniProt: P02281)

PDB	External Database	Details
Thr 32	Ser 33	variant

B: 1 - 100 (UniProt: Q75PQ8)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	285906.4
All*	Total formula weight	285906.4

*Water molecules are not included.