8SIT
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.24 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Spike protein S1 | polymer | 205 | 23104.9 | 4 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | E, G, I, K (H, M, O, Q) | CC84.24 fab heavy chain | polymer | 231 | 24752.7 | 4 | Homo sapiens (human) | ||
| 3 | F, H, J, L (L, N, P, S) | CC84.24 fab light chain | polymer | 214 | 22715.0 | 4 | Homo sapiens (human) | ||
| 4 | M, N (A, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 333 - 530 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 282290.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 282732.5 |
