8SIT

Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.24 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Spike protein S1	polymer	205	23104.9	4	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H, M, O, Q	CC84.24 fab heavy chain	polymer	231	24752.7	4		Homo sapiens (human)
3	L, N, P, S	CC84.24 fab light chain	polymer	214	22715.0	4		Homo sapiens (human)
4	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, B, C, D: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	282290.1
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	282732.5

*Water molecules are not included.