8SIG
Crystal Structure of PRMT4 with Compound YD1-288
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone-arginine methyltransferase CARM1 | polymer | 359 | 40946.5 | 1 | UniProt (Q86X55) Pfam (PF06325) Pfam (PF22528) In PDB | Homo sapiens (human) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
2 | A | 5'-{(3-aminopropyl)[2-(benzylcarbamamido)ethyl]amino}-5'-deoxyadenosine | non-polymer | 499.6 | 1 | Chemie (GWU) | |||
3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | A | UNKNOWN ATOM OR ION | non-polymer | 7 | Chemie (UNX) | ||||
5 | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A: 140 - 480 (UniProt: Q86X55)
PDB | External Database | Details |
---|---|---|
Met 122 | - | initiating methionine |
His 123 | - | expression tag |
His 124 | - | expression tag |
His 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
Ser 129 | - | expression tag |
Ser 130 | - | expression tag |
Gly 131 | - | expression tag |
Arg 132 | - | expression tag |
Glu 133 | - | expression tag |
Asn 134 | - | expression tag |
Leu 135 | - | expression tag |
Tyr 136 | - | expression tag |
Phe 137 | - | expression tag |
Gln 138 | - | expression tag |
Gly 139 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40946.5 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 522.6 | |
All* | Total formula weight | 41469.1 |