8SIC

Crystal structure of Epstein-Barr virus glycoprotein 350 (gp350) in complex with Cy137C02, a monoclonal antibody isolated from macaques immunized with a gp350 nanoparticle vaccine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, H)	Cy137C02 Fab heavy chain	polymer	222	23805.8	2		Macaca fascicularis
2	B, F (B, L)	Cy137C02 Fab light chain	polymer	215	22806.2	2		Macaca fascicularis
3	C, D (E, G)	Envelope glycoprotein gp350	polymer	431	46895.2	2	UniProt (P03200) Pfam (PF05109) Pfam (PF20676) Pfam (PF20677)	Human herpesvirus 4 (Epstein-Barr virus)	Membrane antigen,MA
4	G, H, I, J, K... (E, G)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	17	Chemie (NAG)
5	M, Y (E, G)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	AA, BA, CA, DA, EA... (B, E, G, H, L...)	water	water		18.0	116	Chemie (HOH)

Sequence modifications

E, G: 1 - 425 (UniProt: P03200)

PDB	External Database	Details
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	187014.4
Non-Polymers*	Number of molecules	19
	Total formula weight	3891.4
All*	Total formula weight	190905.7

*Water molecules are not included.