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8SI3

Cryo-EM structure of TRPM7 in GDN detergent in apo state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel subfamily M member 7polymer1279146888.94UniProt (Q923J1)
Pfam (PF18139)
Pfam (PF00520)
Pfam (PF16519)
In PDB
Mus musculus (house mouse)Channel-kinase 1,Long transient receptor potential channel 7,LTrpC-7,LTrpC7,Transient receptor potential-phospholipase C-interacting kinase,TRP-PLIK
2B, D, A, C(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.152Chemie (POV)
3D, A, C, BCHOLESTEROLnon-polymer386.74Chemie (CLR)
4B, D, A, C2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diolnon-polymer516.84Chemie (DU0)
5ACALCIUM IONnon-polymer40.11Chemie (CA)
6waterwater18.0160Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight587555.5
Non-Polymers*Number of molecules61
Total formula weight43177.7
All*Total formula weight630733.2
*Water molecules are not included.

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PDB entries from 2024-07-17

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