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8SI2

Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in apo state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily M member 7polymer1279146888.94UniProt (Q923J1)
Pfam (PF18139)
Pfam (PF00520)
Pfam (PF16519)
Mus musculus (house mouse)Channel-kinase 1,Long transient receptor potential channel 7,LTrpC-7,LTrpC7,Transient receptor potential-phospholipase C-interacting kinase,TRP-PLIK
2AA, AB, BA, BB, CA...
(B, C, A, D)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.164Chemie (POV)
3EA, H, PB, WA
(B, A, D, C)
CHOLESTEROLnon-polymer386.74Chemie (CLR)
4GB, OA, R, ZB
(C, B, A, D)
2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diolnon-polymer516.84Chemie (DU0)
5W, X
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
6AC, BC, CC, DC
(A, B, C, D)
waterwater18.0168Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight587555.5
Non-Polymers*Number of molecules74
Total formula weight52304.5
All*Total formula weight639860.0
*Water molecules are not included.

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PDB entries from 2024-10-30

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