8SI2
Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in apo state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily M member 7 | polymer | 1279 | 146888.9 | 4 | UniProt (Q923J1) Pfam (PF18139) Pfam (PF00520) Pfam (PF16519) | Mus musculus (house mouse) | Channel-kinase 1,Long transient receptor potential channel 7,LTrpC-7,LTrpC7,Transient receptor potential-phospholipase C-interacting kinase,TRP-PLIK |
2 | AA, AB, BA, BB, CA... (B, C, A, D) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 64 | Chemie (POV) | |||
3 | EA, H, PB, WA (B, A, D, C) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
4 | GB, OA, R, ZB (C, B, A, D) | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol | non-polymer | 516.8 | 4 | Chemie (DU0) | |||
5 | W, X (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
6 | AC, BC, CC, DC (A, B, C, D) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 587555.5 | |
Non-Polymers* | Number of molecules | 74 |
Total formula weight | 52304.5 | |
All* | Total formula weight | 639860.0 |