8SGN
Crystal structure of Epstein-Barr virus glycoprotein 350 (gp350) in complex with Cy651H02, a monoclonal antibody isolated from macaques immunized with a gp350 nanoparticle vaccine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Cy651H02 Fab light chain | polymer | 214 | 22490.7 | 1 | Macaca fascicularis | ||
| 2 | B (H) | Cy651H02 Fab heavy chain | polymer | 223 | 23765.7 | 1 | Macaca fascicularis | ||
| 3 | C (G) | Envelope glycoprotein gp350 | polymer | 431 | 46895.2 | 1 | UniProt (P03200) Pfam (PF05109) Pfam (PF20676) Pfam (PF20677) | Human herpesvirus 4 (Epstein-Barr virus) | Membrane antigen,MA |
| 4 | D (K) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 5 | E, F, GA, HA, IA... (L, G, H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 23 | Chemie (EDO) | |||
| 6 | G, H, I, R (L, H) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 4 | Chemie (TRS) | |||
| 7 | AA, BA, CA, DA, EA... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 8 | OA, PA, QA (L, H, G) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
G: 1 - 425 (UniProt: P03200)
| PDB | External Database | Details |
|---|---|---|
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
| His 429 | - | expression tag |
| His 430 | - | expression tag |
| His 431 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93151.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 3907.0 | |
| All* | Total formula weight | 97426.0 |
