8SGD

Crystal Structure of CDC3(G) - CDC10(Delta 1-10) heterocomplex from Saccharomyces cerevisiae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	CDC10 isoform 1	polymer	313	36175.8	2	UniProt (A0A8H4BSX4) Pfam (PF00735) UniProt (by SIFTS) (P25342) In PDB	Saccharomyces cerevisiae (baker's yeast)
2	B, D	CDC3 isoform 1	polymer	309	35695.7	2	UniProt (A0A8H4BZN9) Pfam (PF00735) UniProt (by SIFTS) (P32457) In PDB	Saccharomyces cerevisiae (baker's yeast)
3	A, C	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
4	A, B, C, D	SODIUM ION	non-polymer		23.0	13	Chemie (NA)
5	B, D	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	B, D	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7		water	water		18.0	158	Chemie (HOH)

Sequence modifications

A, C: 11 - 322 (UniProt: A0A8H4BSX4)

PDB	External Database	Details
Met 10	-	initiating methionine

B, D: 119 - 413 (UniProt: A0A8H4BZN9)

PDB	External Database	Details
Met 105	-	initiating methionine
Gly 106	-	expression tag
Ser 107	-	expression tag
Ser 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
Ser 115	-	expression tag
Gln 116	-	expression tag
Asp 117	-	expression tag
Pro 118	-	expression tag
Ala 158	Ser 158	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143743.1
Non-Polymers*	Number of molecules	19
	Total formula weight	2280.2
All*	Total formula weight	146023.3

*Water molecules are not included.