8SDM

HTRA-1 PDSA bound to CKP 3B3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Serine protease HTRA1	polymer	240	26060.8	3	UniProt (Q92743) Pfam (PF13365)	Homo sapiens (human)	High-temperature requirement A serine peptidase 1,L56,Serine protease 11
2	D, E, F (I, X, Y)	Cysteine-containing peptide 3B3	polymer	37	4103.6	3		Ecballium elaterium

Sequence modifications

A, B, C: 161 - 379 (UniProt: Q92743)

PDB	External Database	Details
Met 140	-	expression tag
Gly 141	-	expression tag
Ser 142	-	expression tag
Ser 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
Ser 150	-	expression tag
Ser 151	-	expression tag
Gly 152	-	expression tag
Leu 153	-	expression tag
Val 154	-	expression tag
Pro 155	-	expression tag
Arg 156	-	expression tag
Gly 157	-	expression tag
Ser 158	-	expression tag
His 159	-	expression tag
Met 160	-	expression tag
Ala 328	Ser 328	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	90493.3
All*	Total formula weight	90493.3

*Water molecules are not included.