8SDH

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.56

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Spike protein S1	polymer	205	23104.9	2	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H, C	Neutralizing antibody CC25.56 Heavy Chain	polymer	223	23771.9	2		Homo sapiens (human)
3	L, D	Neutralizing antibody CC25.56 Light Chain	polymer	214	22787.1	2		Homo sapiens (human)
4	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6		water	water		18.0	41	Chemie (HOH)

Sequence modifications

A, B: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	139327.8
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	139973.4

*Water molecules are not included.