8SCZ
Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Antiviral innate immune response receptor RIG-I | polymer | 887 | 101823.2 | 1 | UniProt (O95786) Pfam (PF16739) Pfam (PF00270) Pfam (PF18119) Pfam (PF00271) Pfam (PF11648) | Homo sapiens (human) | ATP-dependent RNA helicase DDX58,DEAD box protein 58,RIG-I-like receptor 1,RLR-1,RNA sensor RIG-I,Retinoic acid-inducible gene 1 protein,RIG-1,Retinoic acid-inducible gene I protein,RIG-I |
| 2 | B (B) | p3SLR30 | polymer | 64 | 20709.2 | 1 | Homo sapiens | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 39 - 925 (UniProt: O95786)
| PDB | External Database | Details |
|---|---|---|
| - | Glu 189 | deletion |
| - | Lys 190 | deletion |
| - | Gly 191 | deletion |
| - | Ile 192 | deletion |
| - | Lys 193 | deletion |
| - | Asp 194 | deletion |
| - | Val 195 | deletion |
| - | Glu 196 | deletion |
| - | Thr 197 | deletion |
| - | Glu 198 | deletion |
| - | Asp 199 | deletion |
| - | Leu 200 | deletion |
| - | Glu 201 | deletion |
| - | Asp 202 | deletion |
| - | Lys 203 | deletion |
| - | Met 204 | deletion |
| - | Glu 205 | deletion |
| - | Thr 206 | deletion |
| - | Ser 207 | deletion |
| - | Asp 208 | deletion |
| - | Ile 209 | deletion |
| - | Gln 210 | deletion |
| - | Ile 211 | deletion |
| - | Phe 212 | deletion |
| - | Tyr 213 | deletion |
| - | Gln 214 | deletion |
| - | Glu 215 | deletion |
| - | Asp 216 | deletion |
| - | Pro 217 | deletion |
| - | Glu 218 | deletion |
| - | Cys 219 | deletion |
| - | Gln 220 | deletion |
| - | Asn 221 | deletion |
| - | Leu 222 | deletion |
| - | Ser 223 | deletion |
| - | Glu 224 | deletion |
| - | Asn 225 | deletion |
| - | Ser 226 | deletion |
| Gly 227 | Cys 227 | conflict |
| Ser 228 | Pro 228 | conflict |
| Gly 229 | Pro 229 | conflict |
| Gly 231 | Glu 231 | conflict |
| Ser 232 | Val 232 | conflict |
| Gly 233 | Ser 233 | conflict |
| Ser 234 | Asp 234 | conflict |
| Gly 235 | Thr 235 | conflict |
| Ser 236 | Asn 236 | conflict |
| Gly 237 | Leu 237 | conflict |
| Ser 238 | Tyr 238 | conflict |
| Gly 239 | Ser 239 | conflict |
| Ser 240 | Pro 240 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 122532.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 122597.8 |
