8SC9
Structure of PPARG in complex with MTX-531
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 278 | 31734.9 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | A | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 1 | Chemie (TAM) | |||
| 4 | B | N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide | non-polymer | 453.9 | 1 | Chemie (D0D) | |||
| 5 | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
A, B: 204 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 200 | - | expression tag |
| Ser 201 | - | expression tag |
| His 202 | - | expression tag |
| Met 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63469.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1577.8 | |
| All* | Total formula weight | 65047.5 |
