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8SB8

CryoEM structure of P-Glycoprotein in collapsed closed state with vanadate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-dependent translocase ABCB1polymer1280141644.81UniProt (P08183)
Pfam (PF00664)
Pfam (PF00005)
Homo sapiens (human)ATP-binding cassette sub-family B member 1,Multidrug resistance protein 1,P-glycoprotein 1,Phospholipid transporter ABCB1
2B, C
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
3D, E
(A)
ADP ORTHOVANADATEnon-polymer544.22Chemie (AOV)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight141644.8
Non-Polymers*Number of molecules4
Total formula weight1136.9
All*Total formula weight142781.7
*Water molecules are not included.

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PDB entries from 2025-07-30

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