8SB5
CryoEM structure of DH270.I1.6-CH848.10.17
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, F, K) | CH848.10.17.SOSIP gp120 | polymer | 471 | 52847.9 | 3 | UniProt (A0A1W6IPB2) Pfam (PF00516) | HIV-1 06TG.HT008 | |
| 2 | B, F, J (B, G, L) | CH848.10.17.SOSIP gp41 | polymer | 132 | 14733.7 | 3 | HIV-1 06TG.HT008 | ||
| 3 | C, G, K (C, H, M) | DH270.I1.6 variable heavy chain | polymer | 127 | 14157.7 | 3 | Homo sapiens (human) | ||
| 4 | D, H, L (D, I, N) | DH270.I1.6 variable light chain | polymer | 110 | 11490.7 | 3 | Homo sapiens (human) | ||
| 5 | M, U (E, U) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 6 | N, R, V (J, R, V) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1883.7 | 3 | In PDB GlyTouCan (G60230HH) | |||
| 7 | O, Q, S, W (O, Q, S, W) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 4 | In PDB GlyTouCan (G01760ZU) | |||
| 8 | P, T, X (P, T, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) |
Sequence modifications
A, F, K: 34 - 511 (UniProt: A0A1W6IPB2)
| PDB | External Database | Details |
|---|---|---|
| Ala 31 | - | expression tag |
| Glu 32 | - | expression tag |
| Asn 33 | - | expression tag |
| Cys 201 | Val 189 | conflict |
| Cys 433 | Ala 417 | conflict |
| Lys 490 | Glu 474 | conflict |
| Glu 492 | Gln 476 | conflict |
| Val 496 | Ile 480 | conflict |
| Arg 500 | Gly 484 | conflict |
| Cys 501 | Ala 485 | conflict |
| Gly 507 | Glu 491 | conflict |
| Arg 509 | Glu 493 | conflict |
| Arg 510 | Lys 494 | conflict |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 279690.0 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 13199.9 | |
| All* | Total formula weight | 292889.8 |
