8SAX
CryoEM structure of DH270.UCA-CH848.10.17DT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, E, I) | CH848.10.17.SOSIP gp120 | polymer | 471 | 52835.9 | 3 | UniProt (A0A1W6IPB2) Pfam (PF00516) | HIV-1 06TG.HT008 | |
| 2 | B, F, J (B, F, J) | CH848.10.17.SOSIP gp41 | polymer | 132 | 14733.7 | 3 | Pfam (PF00517) UniProt (by SIFTS) (A0A6H1VLP0) | HIV-1 06TG.HT008 | |
| 3 | C, G, K (C, G, K) | DH270.UCA heavy chain | polymer | 127 | 14110.7 | 3 | Homo sapiens (human) | ||
| 4 | D, H, L (D, H, L) | DH270.UCA light chain | polymer | 111 | 11432.6 | 3 | Homo sapiens (human) | ||
| 5 | M, Q, U (M, Q, U) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 6 | N, R, V (N, R, V) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 3 | In PDB GlyTouCan (G68668TB) | |||
| 7 | O, P, S, T, W... (O, P, S, T, W...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A, E, I: 34 - 511 (UniProt: A0A1W6IPB2)
| PDB | External Database | Details |
|---|---|---|
| Ala 31 | - | expression tag |
| Glu 32 | - | expression tag |
| Asn 33 | - | expression tag |
| Asp 133 | Asn 129 | conflict |
| Thr 138 | Asn 134 | conflict |
| Cys 201 | Val 189 | conflict |
| Cys 433 | Ala 417 | conflict |
| Lys 490 | Glu 474 | conflict |
| Glu 492 | Gln 476 | conflict |
| Val 496 | Ile 480 | conflict |
| Arg 500 | Gly 484 | conflict |
| Cys 501 | Ala 485 | conflict |
| Gly 507 | Glu 491 | conflict |
| Arg 509 | Glu 493 | conflict |
| Arg 510 | Lys 494 | conflict |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 279338.5 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 9470.6 | |
| All* | Total formula weight | 288809.1 |
