8SAV
CryoEM structure of VRC01-CH848.0526.25
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E, I | CH848.0526.25 gp120 | polymer | 487 | 54806.1 | 3 | UniProt (A0A1W6IHA4) Pfam (PF00516) In PDB | HIV-1 06TG.HT008 | |
2 | B, F, J | CH848.0526.25 gp41 | polymer | 153 | 17146.5 | 3 | Pfam (PF00517) UniProt (by SIFTS) (A0A6H1V945) In PDB | HIV-1 06TG.HT008 | |
3 | C, G, K | VRC01 variable heavy chain | polymer | 121 | 13801.7 | 3 | Homo sapiens (human) | ||
4 | D, H, L | VRC01 variable light chain | polymer | 101 | 11100.2 | 3 | Homo sapiens (human) | ||
5 | a, M, N, Q, R... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 9 | In PDB GlyTouCan (G15407YE) | |||
6 | O, T, Y | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
7 | Z, P, U | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
8 | A, E, I | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, E, I: 33 - 509 (UniProt: A0A1W6IHA4)
PDB | External Database | Details |
---|---|---|
Ala 31 | - | expression tag |
Glu 32 | - | expression tag |
Cys 201 | Val 209 | conflict |
Cys 433 | Ala 435 | conflict |
Lys 490 | Glu 493 | conflict |
Glu 492 | Gln 495 | conflict |
Val 496 | Ile 499 | conflict |
Arg 500 | Gly 503 | conflict |
Cys 501 | Ala 504 | conflict |
Gly 507 | Glu 510 | conflict |
Arg 508 | Glu 512 | conflict |
Arg 508 | Lys 513 | conflict |
Arg 510 | - | expression tag |
Arg 511 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 290563.6 | |
Branched | Number of molecules | 15 |
Total formula weight | 9284.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1327.2 | |
All* | Total formula weight | 301175.4 |