8SAT
CryoEM structure of VRC01-CH848.10.17
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, E, I) | CH848.10.17 gp120 | polymer | 471 | 52847.9 | 3 | UniProt (A0A1W6IPB2) Pfam (PF00516) | HIV-1 06TG.HT008 | |
| 2 | B, F, J (B, F, J) | CH848.10.17 gp41 | polymer | 153 | 17146.5 | 3 | HIV-1 06TG.HT008 | ||
| 3 | C, G, K (C, G, K) | VRC01-variable heavy chain | polymer | 121 | 13801.7 | 3 | Homo sapiens (human) | ||
| 4 | D, H, L (D, H, L) | VRC01-variable light chain | polymer | 105 | 11440.6 | 3 | Homo sapiens (human) |
Sequence modifications
A, E, I: 4 - 469 (UniProt: A0A1W6IPB2)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Asn 3 | - | expression tag |
| Cys 163 | Val 189 | conflict |
| Cys 391 | Ala 417 | conflict |
| Lys 448 | Glu 474 | conflict |
| Glu 450 | Gln 476 | conflict |
| Val 454 | Ile 480 | conflict |
| Arg 458 | Gly 484 | conflict |
| Cys 459 | Ala 485 | conflict |
| Gly 465 | Glu 491 | conflict |
| Arg 467 | Glu 493 | conflict |
| Arg 468 | Lys 494 | conflict |
| Arg 470 | - | expression tag |
| Arg 471 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 285710.2 | |
| All* | Total formula weight | 285710.2 |
