8SAL
CryoEM structure of VRC01-CH848.0358.80
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I | CH0848.3.D0358.80.06CHIM.DS.6R.SOSIP gp120 | polymer | 475 | 53415.7 | 3 | UniProt (A0A1W6IG54) Pfam (PF00516) In PDB | HIV-1 06TG.HT008 | |
| 2 | B, F, J | CH0848.3.D0358.80.06CHIM.DS.6R.SOSIP gp41 | polymer | 153 | 17146.5 | 3 | Pfam (PF00517) UniProt (by SIFTS) (A0A6H1V945) In PDB | HIV-1 06TG.HT008 | |
| 3 | C, G, K | VCR01 variable heavy chain | polymer | 121 | 13801.7 | 3 | Homo sapiens (human) | ||
| 4 | D, H, L | VCR01 variable light chain | polymer | 103 | 11270.4 | 3 | Homo sapiens (human) |
Sequence modifications
A, E, I: 4 - 473 (UniProt: A0A1W6IG54)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Asn 3 | - | expression tag |
| Cys 170 | Val 199 | conflict |
| Cys 394 | Ala 423 | conflict |
| Lys 452 | Glu 481 | conflict |
| Glu 454 | Gln 483 | conflict |
| Val 458 | Ile 487 | conflict |
| Arg 462 | Gly 491 | conflict |
| Cys 463 | Ala 492 | conflict |
| Gly 469 | Glu 498 | conflict |
| Arg 471 | Glu 500 | conflict |
| Arg 472 | Lys 501 | conflict |
| Arg 474 | - | expression tag |
| Arg 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 286902.9 | |
| All* | Total formula weight | 286902.9 |
